It may be beneficial to discard high-point cards early in the game, particularly if they don't add to any possible melds. On the other hand, it is usually a good idea to keep cards that have the potentiateen patti joinl to finish a set or sequence since they might gain value as the game goes on. When making discard decisions, players also need to take their opponents' possible hands into account. An opponent may be on the verge of forming a meld if you observe that they are regularly taking cards from the discard pile. It could be wise to keep cards that could help them finish their combinations in these situations.
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