It's important to keep an eye on how your opponents use wild cards in addition to making good use of them in your own hand. It could mean that an opponent slots winner downloadis almost finished with their hand if they play a joker in their melds. You can use this information to help you decide which cards to keep or throw away. Also, if you are given the chance to draw a wild card from the discard pile, think about how it will fit into your overall plan before taking that action.
owb